Analytical Development, Staff to Senior Scientist
Job Code: 3320408.GY.SrSci
We are current looking for an energetic and talented analytical chemist to
join our Analytical Chemistry team. The successful candidate will be a
key team member utilizing advanced analytical instrumentation and
techniques, such as HPLC/UV/PDA/ELSD, LC/MS/MS, GC/MS, NMR, to forward
our exciting drug candidates. This newly created position will report
to the leader of the Analytical Research group within Analytical
Chemistry.
Responsibilities:
- technical leadership in the isolation, structural elucidation and quantification of drug impurities and degradation products;
- performing and developing Mass Spectrometric, Chromatographic, NMR and other analytical techniques to provide full characterization of unknown small molecules;
- writing technical procedures, technical reports and documents in support of our drug development projects;
- optimizing techniques and identifying and implementing new technologies to enhance Analytical capabilities, (for example CE, SFC) with regard to the isolation, monitoring and identification of drug impurities and degradation products;
- performing physical characterization of drug candidates (pH, pKA, solubility) as part of preformulation support;
- managing multiple projects with minimum supervision and meeting internal and external client timelines with respect to data and reports;
- interacting productively with colleagues on multidisciplinary drug development project teams to achieve project goals. Working on complex problems where analysis of situations or data requires an in-depth evaluation of many factors;
- sustained demonstration of leadership qualities in technical proficiency, scientific creativity, collaborations with others and independent thought;
- demonstrating commitment and enhanced efficiency in quantity and quality of work
- maintaining familiarity with scientific literature. Possesses intellectual mastery in Analytical Chemistry.
Qualifications and Other Required Knowledge and Skills:
The ideal candidate should have a PhD or MS degree with at least five - ten
years of relevant experience in GMP analytical method
development/validation and ICH stability testing within the
pharmaceutical industry. Expertise in HPLC and detector technology
(such as UV, ELSD, RI or MS detectors), in modern data acquisition and
in handling software is essential. Experience in development of IVIVC
dissolution methods for IR/CR tablet formulations would be a plus. Good
documentation, people management and communication skills will be
required. Prior experience with analytical development for commercial
or late-stage