A Human Interaction Management System (HIMS) is software that structures human collaboration into adaptive business processes. Such processes, known as Stories, provide helpful structure both to participants and to their organizations, while allowing sufficient flexibility to permit innovative, creative work

In practice, since a HIMS must be able to support collaboration that spans various forms of organizational boundary, the software cannot depend on a server component. Though a HIMS may be able to run on a server if necessary (for instance, to support audit trail recording), it is typically intended for desktop use. A HIMS communicates peer-to-peer both with other instances of itself and with standard communication programs such as email clients in order to synchronize, monitor and support the work of the people involved.

To the average end user, a HIMS appears as a lightweight layer on top of their existing computing resources - other desktop programs, network files, enterprise applications, and Web 2.0 tools of various kinds. The HIMS is effectively a more intelligent desktop interface, enhancing the benefit of every kind of computing resource from emails to databases, by providing a rich process context via which such resources are accessed.

The HIMS concept is based on the theory of Human Interaction Management (HIM). The reference implementation of a HIMS is the free HumanEdj.